In the realm of Industry 4.0, diverse technologies such as AI, Cyber-Physical Systems, IoT, and advanced sensors converge to shape smarter future factories. Mobile manipulators (MMs) are pivotal, fostering flexibility, adaptability, and collaboration in industrial processes. On one hand, MMs offer a remarkable level of flexibility, adaptability, and collaboration in industrial processes, facilitating swift production line changes and efficiency enhancements. On the other hand, their integration into real manufacturing environments requires meticulous considerations, such as safety, human-robot interaction, and cybersecurity. This article delves into MMs' essential role in achieving Industry 4.0's automation and adaptability by integrating mobility with manipulation capabilities. The study reviews MMs' industrial applications and integration into manufacturing systems. The most observed applications are logistics (49%) and manufacturing (33%). As Industry 4.0 advances, the paper emphasizes updating and aligning MMs with the smart factory concept by networks of sensors and the real-time analysis of them, especially for an enhanced human-robot interaction. Another objective is categorizing considerations for MMs' utilization in Industry 4.0-aligned manufacturing. This review methodically covers a wide range of considerations and evaluates existing solutions. It shows a more comprehensive approach to understanding MMs in Industry 4.0 than previous works. Key focus areas encompass perception, data analysis, connectivity, human-robot interaction, safety, virtualization, and cybersecurity. By bringing together different aspects, this research emphasizes a more integrated view of the role and challenges of MMs in the Industry 4.0 paradigm and provides insights into aspects often overlooked. A detailed and synthetic analysis of existing knowledge was performed, and insights into their future path in Industry 4.0 environments were provided as part of the contributions of this paper. The article also appraises initiatives in these domains, along with a succinct technology readiness analysis. To sum up, this study highlights MMs' pivotal role in Industry 4.0, encompassing their influence on adaptability, automation, and efficiency.
Keywords: Industry 4.0; human–robot interaction; mobile manipulators; technology readiness level.