Oxidative status alteration during aerobic-dominant mixed and anaerobic-dominant mixed effort in judokas

Imed Gandouzi; Soufien Fekih; Okba Selmi; Nasr Chalghaf; Mouna Turki; Fatma Ayedi; Noomen Guelmami; Fairouz Azaiez; Nizar Souissi; Santo Marsigliante; Antonella Muscella

doi:10.1016/j.heliyon.2023.e20442

Oxidative status alteration during aerobic-dominant mixed and anaerobic-dominant mixed effort in judokas

Heliyon. 2023 Oct 5;9(10):e20442. doi: 10.1016/j.heliyon.2023.e20442. eCollection 2023 Oct.

Authors

Imed Gandouzi^{1

2

3}, Soufien Fekih², Okba Selmi⁴, Nasr Chalghaf^{2

5}, Mouna Turki^{1

6}, Fatma Ayedi⁶, Noomen Guelmami⁴, Fairouz Azaiez^{2

5}, Nizar Souissi³, Santo Marsigliante⁷, Antonella Muscella⁷

Affiliations

¹ Molecular Basis of Human Pathology Laboratory, Faculty of Medicine of Sfax, Tunisia.
² Higher Institute of Sport and Physical Education of Gafsa ISSEP, Gafsa, Tunisia.
³ RU: Physical Activity, Sport & Health, The National Observatory of Sport, Tunisia.
⁴ Higher Institute of Sport and Physical Education of Kef ISSEP, Kef, Tunisia.
⁵ Group for the Study of Development and Social Environment (GEDES), Faculty of Human and Social Science of Sfax, Sfax, Tunisia.
⁶ Biochemistry Laboratory, Habib Bourguiba Hospital, Sfax, Tunisia.
⁷ Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy.

Abstract

This study aimed to depict the oxidative status variation in judokas during aerobic-dominant mixed effort (AeDME) and anaerobic-dominant mixed effort (AnDME). It is to be expected that the sporting commitment of Judo is a stimulus of oxidative stress leading to the recruitment of antioxidant responses. Blood samples were collected from 17 athletes at rest, immediately after a training session (AeDME) and after a 5-min bout (AnDME). AeDME and AnDME caused significant increases in malondialdehyde (MDA) (p < 0.01 and p < 0.001 respectively) and glutathione (GSH) (p = 0.018 and p < 0.001 respectively). Blood thiol concentrations decreased following AeDME and AnDME (p < 0.001) whilst catalase decreased significantly after AnDME (p = 0.026) only. Uric acid increased significantly after AnDME than after AeDME (p = 0.047) while, conversely, total bilirubin was higher after AnDME than after AeDME (p = 0.02). We may ultimately summarize that AeDME and AnDME caused oxidative stress, higher in AnDME, and some antioxidant response slightly higher in AnDME compared to AeDME. In sports, monitoring of oxidative stress status is recommended as part of the training regimen.

Keywords: Antioxidant response; Bilirubin; Glutathione; Judo; Malondialdehyde; Oxidative stress; Thiol.