A focus on harnessing big data and artificial intelligence: revolutionizing drug discovery from traditional Chinese medicine sources

Mingyu Li; Jian Zhang

doi:10.1039/d3sc90185h

A focus on harnessing big data and artificial intelligence: revolutionizing drug discovery from traditional Chinese medicine sources

Chem Sci. 2023 Sep 26;14(39):10628-10630. doi: 10.1039/d3sc90185h. eCollection 2023 Oct 11.

Authors

Mingyu Li¹, Jian Zhang^{1

2}

Affiliations

¹ State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China jian.zhang@sjtu.edu.cn.
² Medicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine Shanghai 200025 China.

Abstract

The advent of big data-driven artificial intelligence (AI) modeling has profoundly impacted the realm of drug discovery. Chen et al. (Q. Lv et al., Chem. Sci., 2023, https://doi.org/10.1039/D3SC02139D) have paved a way for modern drug discovery from traditional Chinese medicine (TCM) sources through their efforts over the past decade. They achieved this by creating TCMBank, the most extensive systematic central resource for TCM, which integrates standardized TCM-related big data and streamlines the AI-based drug discovery process.