Metal-organic framework composite Mn/Fe-MOF@Pd with peroxidase-like activities for sensitive colorimetric detection of hydroquinone

Die Deng; Ya Wang; Shaohua Wen; Yujie Kang; Xiaoyan Cui; Rong Tang; Xiupei Yang

doi:10.1016/j.aca.2023.341797

Metal-organic framework composite Mn/Fe-MOF@Pd with peroxidase-like activities for sensitive colorimetric detection of hydroquinone

Anal Chim Acta. 2023 Oct 23:1279:341797. doi: 10.1016/j.aca.2023.341797. Epub 2023 Sep 8.

Authors

Die Deng¹, Ya Wang¹, Shaohua Wen², Yujie Kang¹, Xiaoyan Cui³, Rong Tang¹, Xiupei Yang⁴

Affiliations

¹ College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong, 637000, China.
² College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong, 637000, China; School of Chemistry and Chemical Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China. Electronic address: shaohuawen@126.com.
³ College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong, 637000, China; Nanchong Food and Drug Inspection Institute, Nanchong, 637000, China.
⁴ College of Chemistry and Chemical Engineering, Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, China West Normal University, Nanchong, 637000, China. Electronic address: xiupeiyang@cwnu.edu.cn.

PMID: 37827690
DOI: 10.1016/j.aca.2023.341797

Abstract

The construction of highly sensitive detection methods for hydroquinone (HQ) in environment and cosmetics is of great significance for environmental protection and human health. In this work, a novel detection method for HQ was successfully developed by constructing a metal-organic framework mimic enzyme colorimetric sensor (Mn/Fe-MOF@Pd_1.0) with excellent peroxidase-like activity, which was synthesized by doping manganese ions into Fe-MOF by introducing bimetallic active centers, thereby improving the peroxidase-like activity of Fe-MOF, and the acid resistance and stability of Mn/Fe-MOF were improved by supporting palladium (Pd NPs). It is proven that Mn/Fe-MOF@Pd_1.0 promoted the decomposition of hydrogen peroxide (H₂O₂) to generate active species, therefore, oxidized chromogenic substrate discoloration. On this basis, the detection of HQ based on the Mn/Fe-MOF@Pd_1.0 colorimetric sensor was constructed, in which the limit of detection (LOD) was 0.09 μM in the linear range of 0.3-30 μM. Furthermore, Mn/Fe-MOF@Pd_1.0 was successfully used for detecting HQ in hydroquinone whitening cream and actual water samples. The successful synthesis of Mn/Fe-MOF@Pd_1.0 may provide new insights for further study of the enzyme-like activity of metal-organic framework composites, and the constructed facile and sensitive sensor system could broaden the application prospects of HQ detection.

Keywords: Colorimetric analysis; Hydroquinone; Metal-organic framework composite; Mimic enzyme.