Sex differences in a murine model of asthma are time and tissue compartment dependent

PLoS One. 2023 Oct 11;18(10):e0271281. doi: 10.1371/journal.pone.0271281. eCollection 2023.

Abstract

Sexual dimorphism in lung inflammation is both time and tissue compartment dependent. Spatiotemporal variability in sex differences in a murine model of asthma must be accounted for when planning experiments to model the sex bias in allergic inflammation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Asthma*
  • Disease Models, Animal
  • Female
  • Inflammation
  • Lung
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Pneumonia*
  • Sex Characteristics