Adoption of cytoreductive surgery in the management of peritoneal malignancies-Global trends

J Surg Oncol. 2023 Nov;128(6):1021-1031. doi: 10.1002/jso.27448.

Abstract

Cytoreductive surgery (CRS) has now been accepted as an integral component in the management of gastrointestinal and gynecological cancers with peritoneal metastases. Since the adoption of CRS is influenced by access to advanced medical facilities, trained multidisciplinary teams, and funding, there is wide variability in incorporation of CRS into routine clinical practice between high- versus low- and middle-income countries. This review highlights the global trends in the adoption of CRS for peritoneal malignancies with a specific focus on the establishment of CRS programs and barriers to incorporate CRS into routine clinical care in low- and middle-income countries.

Keywords: cytoreduction; global trends; peritoneal malignancies.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols
  • Colorectal Neoplasms* / pathology
  • Combined Modality Therapy
  • Cytoreduction Surgical Procedures
  • Humans
  • Hyperthermia, Induced*
  • Peritoneal Neoplasms* / secondary
  • Peritoneum / pathology
  • Retrospective Studies
  • Survival Rate