Vulvovaginal atrophy in the CRETA study: the healthcare professionals' perception

Gynecol Endocrinol. 2023 Dec;39(1):2264405. doi: 10.1080/09513590.2023.2264405. Epub 2023 Oct 9.

Abstract

Objectives: The objective is to assess the perception of gynecologists regarding patients' adherence to vulvovaginal atrophy (VVA) treatments, to evaluate the gynecologists' opinions on what their patients think about treatment adherence, and to compare the gynecologists' opinions with the patients' own perceptions within the CRETA study.

Methods: Spanish gynecologists who participated in the CRETA study were asked to fill out an online 41-item questionnaire to evaluate their views on VVA management.

Results: From 29 centers across Spain, 44 gynecologists completed the survey. Their mean age was 47.2 years old, two-thirds of them were women, and the average professional experience was over 20 years. According to the gynecologists, the therapy most frequently used by VVA-diagnosed women was vaginal moisturizers (45.5%), followed by local estrogen therapy (36.4%) and ospemifene (18.2%). Nevertheless, ospemifene was viewed as the therapeutic option with the most efficacy, easiest route of administration, shorter time to symptom improvement, lower percentage of dropouts, and higher treatment adherence.

Conclusions: Spanish gynecologists are in general agreement with their patients regarding VVA treatment preferences and the main issues for adherence and effectiveness. However, there is an opportunity for doctor-patient communication improvement. Among the three therapeutic options evaluated, ospemifene is regarded as offering some competitive advantages.

Keywords: Vulvovaginal atrophy; genitourinary syndrome of menopause; gynecologists’ perception; gynecologist–patient relationship; ospemifene; surveys and questionnaires; treatment adherence.

MeSH terms

  • Atrophy / drug therapy
  • Atrophy / pathology
  • Delivery of Health Care
  • Female
  • Gynecologists*
  • Humans
  • Male
  • Middle Aged
  • Perception
  • Postmenopause
  • Tamoxifen* / therapeutic use
  • Treatment Adherence and Compliance
  • Vagina* / pathology
  • Vaginal Diseases* / drug therapy
  • Vaginal Diseases* / pathology
  • Vulva* / pathology

Substances

  • Ospemifene
  • Tamoxifen