Hydrogels: An overview of its classifications, properties, and applications

J Mech Behav Biomed Mater. 2023 Nov:147:106145. doi: 10.1016/j.jmbbm.2023.106145. Epub 2023 Sep 28.

Abstract

The review paper starts with the introduction to hydrogels along with broad literature survey covering different modes of synthesis including high energy radiation methods. After that, paper covered broad classification of the hydrogels depending upon the basis of their source of origin, method of synthesis, type of cross-linking present and ionic charges on bound groups. Another advanced category response triggered hydrogels, which includes pH, temperature, electro, and light and substrate responsive hydrogels was also studied. Presented paper summarises chemical structure, properties, and synthesis of different kinds of hydrogels. Main focus was given to the preparation super absorbents such as: Semi-interpenetrating networks (semi-IPNs), Interpenetrating networks (IPNs) and cross-linked binary graft copolymers (BGCPs). The weak mechanical properties and easy degradation limit the uses of bio-based -hydrogels in biomedical field. Their properties can be improved through different chemical and physical methods. These methods were also discussed in the current research paper. Also, it includes development of hydrogels as controlled drug delivery devices, as implants and biomaterials to replace malfunctioned body parts along with their use in several other applications listed in the literature. Literature survey on the application of hydrogels in different fields like biomedical, nano-biotechnology, tissue engineering, drug delivery and agriculture was also carried out.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials* / chemistry
  • Drug Delivery Systems
  • Hydrogels* / chemistry
  • Polymers / chemistry
  • Temperature

Substances

  • Hydrogels
  • Biocompatible Materials
  • Polymers