Sleeping monsters: chronic infections in COVID-19 pathogenesis

Sara Beros; Lena Pernas

doi:10.1016/j.tim.2023.09.008

Sleeping monsters: chronic infections in COVID-19 pathogenesis

Trends Microbiol. 2024 Jan;32(1):10-12. doi: 10.1016/j.tim.2023.09.008. Epub 2023 Oct 2.

Authors

Sara Beros¹, Lena Pernas²

Affiliations

¹ Max Planck Institute for Biology of Ageing, Cologne, Germany.
² Max Planck Institute for Biology of Ageing, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Cologne, Germany; Department of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, CA, USA. Electronic address: lfpernas@mednet.ucla.edu.

PMID: 37793974
DOI: 10.1016/j.tim.2023.09.008

Abstract

We each harbor several chronic infections that can reactivate in response to various stressors and cause serious disease. In this forum article, we consider the reactivation of chronic microbial infections in the context of COVID-19.

Keywords: CMV; COVID-19 disease; EBV; Toxoplasma; chronic microbial and viral infections; herpesviruses.

MeSH terms

COVID-19*
Cytomegalovirus
Cytomegalovirus Infections*
Epstein-Barr Virus Infections*
Herpesviridae Infections*
Herpesvirus 4, Human
Humans
Persistent Infection