Restricting mealtime ameliorates neurodegeneration

Xiao Tian; David A Sinclair

doi:10.1016/j.cmet.2023.09.006

Restricting mealtime ameliorates neurodegeneration

Cell Metab. 2023 Oct 3;35(10):1673-1674. doi: 10.1016/j.cmet.2023.09.006.

Authors

Xiao Tian¹, David A Sinclair²

Affiliations

¹ Paul F. Glenn Center for Biology of Aging Research, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: xiaotian@sbpdiscovery.org.
² Paul F. Glenn Center for Biology of Aging Research, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: david_sinclair@hms.harvard.edu.

PMID: 37793341
DOI: 10.1016/j.cmet.2023.09.006

Abstract

Alzheimer's disease is often accompanied by disruptions in circadian rhythms, which may exacerbate the disease's progression. In this issue, Whittaker and colleagues demonstrate that the modulation of circadian rhythms by time-restricted feeding can alter the disease trajectory in Alzheimer's mouse models.

Published by Elsevier Inc.

Publication types

Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Comment

MeSH terms

Alzheimer Disease*
Animals
Circadian Rhythm*
Disease Models, Animal
Meals
Mice

Abstract

Publication types

MeSH terms

Grants and funding