Vaccine-induced anaphylaxis in a child with cow's milk allergy: Lactose hydrate was the culprit

Shoko Yoshino; Yukiko Hiraguchi; Mari Tatekawa; Tomoya Shingaki; Yusuke Kumagai; Yuko Ebishima; Takahiro Kiyomasu; Kenji Owa; Yutaka Suehiro; Mizuho Nagao; Takao Fujisawa

doi:10.1016/j.jacig.2022.01.003

Vaccine-induced anaphylaxis in a child with cow's milk allergy: Lactose hydrate was the culprit

J Allergy Clin Immunol Glob. 2022 Mar 9;1(2):87-89. doi: 10.1016/j.jacig.2022.01.003. eCollection 2022 May.

Authors

Shoko Yoshino^{1

2}, Yukiko Hiraguchi^{1

3}, Mari Tatekawa¹, Tomoya Shingaki^{1

4}, Yusuke Kumagai¹, Yuko Ebishima⁵, Takahiro Kiyomasu¹, Kenji Owa¹, Yutaka Suehiro¹, Mizuho Nagao³, Takao Fujisawa³

Affiliations

¹ Center of Allergy and Clinical Immunology, Department of Pediatrics, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.
² Department of Pediatrics, Kobe City Hospital Organization Kobe City Medical Center West Hospital, Kobe, Japan.
³ Institute for Clinical Research, Allergy Center, National Hospital Organization Mie National Hospital, Tsu, Japan.
⁴ Department of Pediatrics, Naha City Hospital, Naha, Japan.
⁵ Kamesaki Children and Allergy Clinic, Toyonaka, Japan.

Abstract

Lactose hydrate was the cause of vaccine-induced anaphylaxis in a child with severe milk allergy. Although the amount of milk protein in lactose-containing vaccines is extremely small, physicians administering such a vaccine must be prepared for the potential risk of severe milk allergy.

Keywords: Anaphylaxis; Japanese encephalitis vaccine; cow's milk allergy; lactose hydrate.

Publication types

Case Reports