InCl3-catalyzed intramolecular carbonyl-olefin metathesis

Org Biomol Chem. 2023 Oct 18;21(40):8141-8151. doi: 10.1039/d3ob01170d.

Abstract

An efficient and novel synthetic strategy for the generation of different carbocyclic moieties by ring closing carbonyl-olefin metathesis is reported. Herein, we describe a sustainably attractive protocol for one of the most powerful carbon-carbon bond-forming reactions, based on solvent-reduction, use of InCl3 catalyst, and microwave irradiation, affording target compounds with yields up to 96%.