Applications of flexible electronics related to cardiocerebral vascular system

Runxing Lin; Ming Lei; Sen Ding; Quansheng Cheng; Zhichao Ma; Liping Wang; Zikang Tang; Bingpu Zhou; Yinning Zhou

doi:10.1016/j.mtbio.2023.100787

Applications of flexible electronics related to cardiocerebral vascular system

Mater Today Bio. 2023 Aug 30:23:100787. doi: 10.1016/j.mtbio.2023.100787. eCollection 2023 Dec.

Authors

Runxing Lin^{1

2}, Ming Lei¹, Sen Ding¹, Quansheng Cheng¹, Zhichao Ma³, Liping Wang², Zikang Tang¹, Bingpu Zhou¹, Yinning Zhou^{1

4}

Affiliations

¹ Joint Key Laboratory of the Ministry of Education, Institute of Applied Physics and Materials Engineering, University of Macau, Avenida da Universidade, Taipa, Macau, 999078, China.
² Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
³ Institute of Medical Robotics, School of Biomedical Engineering, Shanghai Jiao Tong University, No.800 Dongchuan Road, Shanghai, 200240, China.
⁴ Department of Physics and Chemistry, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau, 999078, China.

Abstract

Ensuring accessible and high-quality healthcare worldwide requires field-deployable and affordable clinical diagnostic tools with high performance. In recent years, flexible electronics with wearable and implantable capabilities have garnered significant attention from researchers, which functioned as vital clinical diagnostic-assisted tools by real-time signal transmission from interested targets in vivo. As the most crucial and complex system of human body, cardiocerebral vascular system together with heart-brain network attracts researchers inputting profuse and indefatigable efforts on proper flexible electronics design and materials selection, trying to overcome the impassable gulf between vivid organisms and rigid inorganic units. This article reviews recent breakthroughs in flexible electronics specifically applied to cardiocerebral vascular system and heart-brain network. Relevant sensor types and working principles, electronics materials selection and treatment methods are expounded. Applications of flexible electronics related to these interested organs and systems are specially highlighted. Through precedent great working studies, we conclude their merits and point out some limitations in this emerging field, thus will help to pave the way for revolutionary flexible electronics and diagnosis assisted tools development.

Publication types

Review