Application of Advanced Technologies-Nanotechnology, Genomics Technology, and 3D Printing Technology-In Precision Anesthesia: A Comprehensive Narrative Review

Pharmaceutics. 2023 Sep 6;15(9):2289. doi: 10.3390/pharmaceutics15092289.

Abstract

There has been increasing interest and rapid developments in precision medicine, which is a new medical concept and model based on individualized medicine with the joint application of genomics, bioinformatics engineering, and big data science. By applying numerous emerging medical frontier technologies, precision medicine could allow individualized and precise treatment for specific diseases and patients. This article reviews the application and progress of advanced technologies in the anesthesiology field, in which nanotechnology and genomics can provide more personalized anesthesia protocols, while 3D printing can yield more patient-friendly anesthesia supplies and technical training materials to improve the accuracy and efficiency of decision-making in anesthesiology. The objective of this manuscript is to analyze the recent scientific evidence on the application of nanotechnology in anesthesiology. It specifically focuses on nanomedicine, precision medicine, and clinical anesthesia. In addition, it also includes genomics and 3D printing. By studying the current research and advancements in these advanced technologies, this review aims to provide a deeper understanding of the potential impact of these advanced technologies on improving anesthesia techniques, personalized pain management, and advancing precision medicine in the field of anesthesia.

Keywords: 3D printing; algology; anesthesia; anesthetic safety; genomics; nanotechnology; precision medicine.

Publication types

  • Review

Grants and funding

This work was supported by National Natural Science Foundation of China (82202071), Sichuan Provincial Science and Technology Program (2022YFS0301, 2023YFS0036), China International Medical Foundation (Z-2018-35-2004), Medical Research Project of Sichuan Province (S20025), Clinical and Translational Research Foundation of Sichuan Provincial People’s Hospital (2021LY18), Chengdu Science and Technology Program (2021-YF05-00640-SN), and Natural Science Research Fund of Higher Education Institutions in Jiangsu Province (22KJA320007).