Spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn: a case report

BMC Ophthalmol. 2023 Sep 26;23(1):395. doi: 10.1186/s12886-023-03135-5.

Abstract

Background: To report the spontaneous regression of an isolated retinal astrocytic hamartoma in a newborn. During the seven-month follow-up duration, fundus photography and fluorescein angiography examinations were performed.

Case presentation: An isolated retinal astrocytic hamartoma was detected in the nasal retina of the left eye of a 4-day-old male infant. At the time of initial presentation, we detected a solitary yellowish-white flat mass with an approximate size of 1.5 disc diameters in the nasal retina. Fluorescein angiography (FA) revealed a diffuse hyperfluorescence with slight fluorescence leakage. Seven months later, the fundus examination showed no lesion in the left eye, FA revealed mild tortuous vessels without leakage.

Conclusions: In the present case, we established that the isolated retinal astrocytic hamartoma in this infant has underwent spontaneous regression. This case can point out that follow -up reexaminations are advisable for a solitary yellowish-white flat mass of the fundus in a newborn.

Keywords: Newborn; Retinal astrocytic hamartoma; Spontaneous regression.

Publication types

  • Case Reports

MeSH terms

  • Fluorescein Angiography
  • Fundus Oculi
  • Hamartoma* / diagnosis
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Physical Examination
  • Retina*