Combination of Fractional Er:YAG Laser, Pulsed Dye Laser, and Intralesional Triamcinolone With 5-Fluorouracil for Keloid Treatment

Bonnie Yudistha Anggawirya; Putri Hendria Wardhani; Diah Mira Indramaya; Muhammad Yulianto Listiawan

doi:10.34172/jlms.2023.30

Combination of Fractional Er:YAG Laser, Pulsed Dye Laser, and Intralesional Triamcinolone With 5-Fluorouracil for Keloid Treatment

J Lasers Med Sci. 2023 Aug 29:14:e30. doi: 10.34172/jlms.2023.30. eCollection 2023.

Authors

Bonnie Yudistha Anggawirya¹, Putri Hendria Wardhani¹, Diah Mira Indramaya¹, Muhammad Yulianto Listiawan¹

Affiliation

¹ Department of Dermatology and Venereology, Faculty of Medicine, Airlangga University, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Abstract

Introduction: Benign fibroproliferative scars that are larger than the initial lesion are called keloids. Keloids treatment in clinical practice is still difficult. Although there are various therapy choices, none is embraced by everyone or is relapse-free. Various treatment modalities such as intralesional corticosteroid injection with 5-fluorouracil (5-FU), fractional Er:YAG laser, pulsed dye laser (PDL), and others can be used either as monotherapies or combined therapies. Therefore, efforts should be made to select the treatment that will provide the best results. Case Presentation: A 6-year-old boy with keloids on the lower lips extending to the chin was successfully treated with a 2940-nm fractional Er:YAG laser alternated with a 595-nm long-PDL followed by the combined intralesional injection of corticosteroid and 5-FU. The patient was followed up for 1 year with no lesion recurrence. Conclusion: Our case supports a combined therapy to successfully treat a patient with a keloid on the chin. Therapy using a combination of these four modalities seems safe and effective and may have a synergistic effect with minimal downtime.

Keywords: 5-Fluorouracil; Er:YAG laser; Intralesional; Keloid; Pulsed dye laser.

Publication types

Case Reports