Exogenous nanoselenium alleviates imidacloprid-induced oxidative stress toxicity by improving phenylpropanoid metabolism and antioxidant defense system in Perilla frutescens (L.) Britt

Qinyong Dong; Dong Li; Yangliu Wu; Chunran Zhou; Yongxi Lin; Peijuan Miao; Jiaqi Li; Canping Pan

doi:10.1016/j.jplph.2023.154095

Exogenous nanoselenium alleviates imidacloprid-induced oxidative stress toxicity by improving phenylpropanoid metabolism and antioxidant defense system in Perilla frutescens (L.) Britt

J Plant Physiol. 2023 Oct:289:154095. doi: 10.1016/j.jplph.2023.154095. Epub 2023 Sep 16.

Authors

Qinyong Dong¹, Dong Li², Yangliu Wu¹, Chunran Zhou¹, Yongxi Lin¹, Peijuan Miao¹, Jiaqi Li¹, Canping Pan³

Affiliations

¹ Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.
² Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, China.
³ Innovation Center of Pesticide Research, Department of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China; Key Laboratory of National Forestry and Grassland Administration on Pest Chemical Control (China Agricultural University), China. Electronic address: canpingp@cau.edu.cn.

PMID: 37741053
DOI: 10.1016/j.jplph.2023.154095

Abstract

Few studies have been conducted to investigate the impact of pesticides on the secondary metabolism of traditional Chinese medicine and strategies to mitigate the toxicity of pesticide-induced oxidative stress. The current study focuses on evaluating the potential impacts of nano selenium (NSe) and imidacloprid (IMI) on the quality, physiological biochemistry, and secondary metabolites in Perilla frutescens (L.) Britt. (P. frutescens). The study utilized metabolome analysis to explore the toxicity mechanism of IMI. The study noted that IMI-induced stress could emerge with detrimental effects by targeting the destruction of the phenylpropanoid biosynthesis pathway. IMI-induced phenylpropanoid metabolism disorder resulted in an 8%, 17%, 25%, 10%, 65%, and 29% reduction in phenylalanine, coniferyl aldehyde, ferulic acid, cafestol, p-coumaraldehyde, and p-coumaric acid levels, respectively. Under the treatment of exogenous NSe, the levels of these metabolites were increased by 16%, 32%, 22%, 22%, 92%, and 29%, respectively. The application of exogenous NSe increased the levels of these metabolites and improved the biochemical disorder and quality of P. frutescens leaves by optimizing the phenylpropanoid metabolic pathway and enhancing the antioxidant system. Overall, the results suggest that foliar application of NSe could alleviate the oxidative stress toxicity induced by IMI and improve the quality of P. frutescens.

Keywords: Biomarker; Nano-selenium; Perilla frutescens (L.) Britt; Pesticide stress; Phenylpropanoid metabolism; Quality.