New Insights into the Applications of 3D-Printed Biomaterial in Wound Healing and Prosthesis

AAPS PharmSciTech. 2023 Sep 19;24(7):191. doi: 10.1208/s12249-023-02643-3.

Abstract

Recently three-dimensional bioprinting (3D-bioP) has emerged as a revolutionary technique for numerous biomedical applications. 3D-bioP has facilitated the printing of advanced and complex human organs resulting in satisfactory therapeutic practice. One of the important biomedical applications of 3D-bioP is in tissue engineering, wound healing, and prosthetics. 3D-bioP is basically aimed to restore the natural extracellular matrix of human's damage due to wounds. The relevant search was explored using various scientific database, viz., PubMed, Web of Science, Scopus, and ScienceDirect. The objective of this review is to emphasize interpretations from the pre-executed studies and to assess the worth of employing 3D-bioP in wound healing as well as prosthetics in terms of patient compliance, clinical outcomes, and economic viability. Furthermore, the benefits of applying 3D-bioP in wound healing over traditional methods have been covered along with the biocompatible biomaterials employed as bioinks has been discussion. Additionally, the review expands about the clinical trials in 3D-bioP field, showing promise of biomedical applicability of this technique with growing advancement in recent years.

Keywords: bioinks; biomedical; prosthetics; skin regeneration; tissue engineering; wound dressings.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials
  • Databases, Factual
  • Humans
  • Printing, Three-Dimensional
  • Prostheses and Implants*
  • Wound Healing*

Substances

  • Biocompatible Materials