Facile preparation of biomimetic mineralized COFs based on magnetic silk fibroin and its effective extraction of sulforaphane from cruciferous vegetables

Guangyang Liu; Xuan Zhang; Jian Wang; Lingyun Li; Jiayong Cao; Chen Yin; Yuan Liu; Ge Chen; Jun Lv; Xiaomin Xu; Jing Wang; Xiaodong Huang; Donghui Xu

doi:10.1016/j.foodchem.2023.137482

Facile preparation of biomimetic mineralized COFs based on magnetic silk fibroin and its effective extraction of sulforaphane from cruciferous vegetables

Food Chem. 2024 Feb 15:434:137482. doi: 10.1016/j.foodchem.2023.137482. Epub 2023 Sep 15.

Authors

Guangyang Liu¹, Xuan Zhang², Jian Wang³, Lingyun Li⁴, Jiayong Cao⁵, Chen Yin⁶, Yuan Liu⁷, Ge Chen⁸, Jun Lv⁹, Xiaomin Xu¹⁰, Jing Wang¹¹, Xiaodong Huang¹², Donghui Xu¹³

Affiliations

¹ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China; Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China. Electronic address: liuguangyang@caas.cn.
² State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China; Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China; Southwest University, Chongqing 400715, China. Electronic address: zhangxuan9864@163.com.
³ Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China. Electronic address: xuanyuanjian0228@126.com.
⁴ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China. Electronic address: lilingyun@caas.cn.
⁵ Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China. Electronic address: cjy244187@163.com.
⁶ Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China. Electronic address: yinchen0425@163.com.
⁷ Hebei Key Laboratory of Quality and Safety Analysis-Testing for Agro-Products and Food, Hebei North University, Zhangjiakou 075000, China. Electronic address: liuyuanwenwen1981@126.com.
⁸ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China. Electronic address: chenge@caas.cn.
⁹ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China. Electronic address: lvjun02@caas.cn.
¹⁰ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China.
¹¹ Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agro-Product Quality and Safety, Ministry of Agriculture Beijing, 100081 Beijing, China. Electronic address: w_jing2001@126.com.
¹² State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China. Electronic address: huangxiaodong@caas.cn.
¹³ State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Key Laboratory of Vegetables Quality and Safety Control, Ministry of Agriculture and Rural Affairs of China, Beijing 100081, China; Southwest University, Chongqing 400715, China. Electronic address: xudonghui@caas.cn.

PMID: 37722339
DOI: 10.1016/j.foodchem.2023.137482

Abstract

A novel biomimetic mineralized covalent organic framework (BM-COF) was prepared based on magnetic silk fibroin and a new sulforaphane pretreatment technology was constructed. First, metal coordination was performed on the surface of silk fibroin, and nanoparticles were deposited by in-situ mineralization after co-precipitation. Then, biomineralized COFs were prepared by in-situ self-assembly of a COF layer on Fe₃O₄@silk fibroin surface guided by interfacial directional growth technology. The BM-COFs had a multilayer structure, large specific surface area and pore volume, and superparamagnetic properties, which make them an ideal adsorbent. The adsorption of sulforaphane by BM-COFs is mainly multi-molecular layer adsorption and chemisorption, there might be electrostatic action, π-stacking and hydrogen bonding in the adsorption process. The composite material was successfully used for the pretreatment of sulforaphane in cruciferous vegetables. An extraction time of 30 min gave extraction efficiencies as high as 92%, and the recovery could reach more than 73%.

Keywords: Biomimetic mineralization; Covalent organic framework; Magnetic solid-phase extraction; Silk fibroin; Sulforaphane.

MeSH terms

Adsorption
Biomimetics
Fibroins* / chemistry
Magnetic Phenomena
Solid Phase Extraction
Vegetables

Substances

Fibroins
sulforaphane