The high burden of pediatric cystic echinococcosis in Kazakhstan: epidemiological and clinical consequences

Trans R Soc Trop Med Hyg. 2023 Dec 4;117(12):875-877. doi: 10.1093/trstmh/trad065.

Abstract

Background: Cystic echinococcosis (CE) is attributable to Echinococcus granulosus metacestodes. Ultrasound examinations enable a stage-specific approach to CE management. However, this approach is not often applied in endemic areas, which include Kazakhstan.

Methods: We collected clinical and ultrasound data on CE pediatric patients seen at a national referral surgical center in Almaty, Kazakhstan, during 2015-2020.

Results: We included 49 patients, and 79 cysts that were all surgically treated. All but one patient carried active cysts (CE1-CE3 stages). Twenty-six (53.2%) did not receive albendazole postsurgery. Children with CE1 and CE3a cysts underwent surgery, while the use of albendazole and percutaneous drainage were advised upon by experts.

Conclusions: A stage-specific approach to CE management in Kazakhstan is urgent, especially in the pediatric population. The rate of active cysts suggests continuing transmission of CE.

Keywords: central Asia; children; clinical management; cystic echinococcosis; disease burden.

MeSH terms

  • Albendazole / therapeutic use
  • Animals
  • Child
  • Cysts*
  • Echinococcosis* / drug therapy
  • Echinococcosis* / epidemiology
  • Echinococcus granulosus*
  • Humans
  • Kazakhstan / epidemiology

Substances

  • Albendazole