Molecular docking analysis of Aza compounds with the heme-binding protein from Tannerella Forsythia

Janani Sathiamurthy; Gayathri Rengasamy; Surya Sankaran; Kavitha Sankaran; Vishnu Priya Veeraraghavan; Rajalakshmanan Eswaramoorthy

doi:10.6026/97320630019053

Molecular docking analysis of Aza compounds with the heme-binding protein from Tannerella Forsythia

Bioinformation. 2023 Jan 31;19(1):53-56. doi: 10.6026/97320630019053. eCollection 2023.

Authors

Janani Sathiamurthy¹, Gayathri Rengasamy¹, Surya Sankaran², Kavitha Sankaran¹, Vishnu Priya Veeraraghavan¹, Rajalakshmanan Eswaramoorthy²

Affiliations

¹ Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-600077.
² Department of Biomaterials (Green lab), Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-600077.

Abstract

The high biological activity and interesting optical properties of the aza compounds is known. Therefore, it is of interest to document the molecular docking analysis data of Aza compounds with the heme-binding protein from an anaerobic, Gram-negative bacterium Tannerella Forsythia. Hence, we report the optimal binding features of Aza compounds with the heme-binding protein from Tannerella Forsythia for further consideration in drug discovery against the pathogen.

Keywords: Aza compounds; Molecular docking; Tannerella Forsythia; anti-microbial agents; drug discovery.