Cardiac Arrest Bundle of cARE Trial (CABARET) survey of current UK neuroprotective CPR practice

James Raitt; Emma Maxwell; James Plumb; Martina Brown; Helen Pocock; Julian Hannah; Charles Deakin

doi:10.1016/j.resplu.2023.100472

Cardiac Arrest Bundle of cARE Trial (CABARET) survey of current UK neuroprotective CPR practice

Resusc Plus. 2023 Sep 12:16:100472. doi: 10.1016/j.resplu.2023.100472. eCollection 2023 Dec.

Authors

James Raitt¹, Emma Maxwell¹, James Plumb^{2

3}, Martina Brown⁴, Helen Pocock⁴, Julian Hannah^{2

3}, Charles Deakin^{3

4}

Affiliations

¹ Thames Valley Air Ambulance, United Kingdom.
² Hampshire and Isle of Wight Air Ambulance, United Kingdom.
³ University Hospital Southampton NHS Foundation Trust, United Kingdom.
⁴ South Central Ambulance NHS Foundation Trust, United Kingdom.

Abstract

Despite low out of hospital cardiac arrest (OOHCA) survival rates within the UK, animal studies hint at improved cerebral blood flow via a bundled neuroprotective CPR approach. The CABARET study introduces three key devices: the Head Up Position (HUP), Active Compression/Decompression (ACD) CPR, and the Impedance Threshold Device (ITD). A survey involving 27 UK pre-hospital critical care services indicated none are using these interventions widely, either alone or bundled. The CABARET team is now initiating a pilot study to investigate the feasibility of this CPR bundle, aiming to fill the prevailing evidence void in resuscitation research.

Keywords: Active compression/decompression CPR (ACE); Head Up CPR (HUP); Impedance Threshold Device (ITD); Neuroprotective CPR.