Recent chemical synthesis of plant polysaccharides

Xiufang Wang; Guozhi Xiao

doi:10.1016/j.cbpa.2023.102387

Recent chemical synthesis of plant polysaccharides

Curr Opin Chem Biol. 2023 Dec:77:102387. doi: 10.1016/j.cbpa.2023.102387. Epub 2023 Sep 14.

Authors

Xiufang Wang¹, Guozhi Xiao²

Affiliations

¹ Department of Chemistry, Kunming University, 2 Puxing Road, Kunming 650214, China.
² State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650201, China. Electronic address: xiaoguozhi@mail.kib.ac.cn.

PMID: 37716049
DOI: 10.1016/j.cbpa.2023.102387

Abstract

Here, chemical syntheses of long, branched and complex glycans over 10-mer from plants are summarized, which highlights amylopectin 20-mer from starch, 17-mer from carthamus tinctorius, α-glucan 30-mer from Longan, 19-mer from psidium guajava and 11-mer from dendrobium huoshanense. The glycans assembly strategies, protecting groups utilization and glycosylation methods discussed here will inspire the efficient synthesis of diverse complex glycans with many 1,2-cis glycosidic linkages.

Keywords: Automated assembly; Glycosylation; One-pot assembly; Plant glycan; Synthesis.

Publication types

Review

MeSH terms

Glycosides
Glycosylation
Plants*
Polysaccharides*

Substances

Polysaccharides
Glycosides