Preclinical activity of a novel multi-axis inhibitor in aggressive and indolent B-cell malignancies

Leuk Lymphoma. 2023 Dec;64(14):2333-2337. doi: 10.1080/10428194.2023.2256914. Epub 2023 Sep 14.
No abstract available

Keywords: Mantle cell lymphoma; chronic lymphocytic leukemia; ibrutinib-resistance; novel BTK/PI3K/BRD4 inhibitor; targeted multi-axis treatment.

MeSH terms

  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell* / pathology
  • Lymphoma, Mantle-Cell* / pathology
  • Protein Kinase Inhibitors / pharmacology
  • Protein-Tyrosine Kinases

Substances

  • Protein-Tyrosine Kinases
  • Protein Kinase Inhibitors