Sex and Racial Disparities in Peripheral Artery Disease

Arterioscler Thromb Vasc Biol. 2023 Nov;43(11):2099-2114. doi: 10.1161/ATVBAHA.123.319399. Epub 2023 Sep 14.

Abstract

Several studies have shown that women and racial and ethnic minority patients are at increased risk of developing lower extremity peripheral artery disease and suffering adverse outcomes from it, but a knowledge gap remains regarding the underlying causes of these increased risks. Both groups are more likely to be underdiagnosed, have poorly managed contributory comorbidities, and incur disparities in treatment and management postdiagnosis. Opportunities for improvement in the care of women and racial and ethnic minorities with peripheral artery disease include increased rates of screening, higher rates of clinical suspicion (particularly in the absence of typical symptoms of intermittent claudication), and more aggressive risk factor management before and after the diagnosis of peripheral artery disease.

Keywords: cardiovascular diseases; coronary artery disease; ethnic and racial minorities; lipoprotein; myocardial infarction; peripheral artery disease.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Ethnicity*
  • Female
  • Healthcare Disparities
  • Humans
  • Minority Groups
  • Peripheral Arterial Disease* / diagnosis
  • Peripheral Arterial Disease* / therapy
  • Racial Groups
  • United States / epidemiology