Identification of the novel HLA-B*15:270 allele by Sanger dideoxy nucleotide sequencing

HLA. 2023 Dec;102(6):756-758. doi: 10.1111/tan.15227. Epub 2023 Sep 13.

Authors

Jian-Ping Li^{1

2

3

4

5

6}, Ying Liu⁵, Xu Zhang^{1

2

3}, Ying-Dong Wei^{1

2

3}, Xiao-Feng Li^{1

2

3

4}

Affiliations

¹ Transfusion Medicine Institute, Liaoning Blood Center, Shenyang, Liaoning, China.
² Liaoning Provincial Key Laboratory for Blood Safety Research, Shenyang, Liaoning, China.
³ Key Laboratory of Blood Safety Research of Shenyang, Shenyang, Liaoning, China.
⁴ Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, Liaoning, China.
⁵ Transfusion Medicine Institute, Harbin Blood Center, Harbin, Heilongjiang, China.
⁶ Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu, China.

PMID: 37702112
DOI: 10.1111/tan.15227

Abstract

HLA-B*15:270 differs from HLA-B*15:12:01 by one nucleotide substitution at position 679 in exon 4.

Keywords: HLA-B*15:270; Sanger dideoxy nucleotide sequencing; a novel allele.

© 2023 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Base Sequence
Exons / genetics
HLA-B Antigens* / genetics
Humans
Nucleotides*
Sequence Analysis, DNA

Substances

HLA-B Antigens
Nucleotides