Comparative study of the etiology of nosocomial bacteremic pneumonia in ventilated and non-ventilated patients: a 10-year experience in an institution

Microbiol Spectr. 2023 Dec 12;11(6):e0151723. doi: 10.1128/spectrum.01517-23. Epub 2023 Sep 12.

Abstract

This study on bacteremic nosocomial pneumonia (bNP) demonstrates the importance of this condition both in patients undergoing and not undergoing mechanical ventilation. Staphylococcus aureus, Enterobacterales, and non-fermenting Gram-negative bacilli are all causative agents in ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP), with a predominance of S. aureus in HAP and of Pseudomonas aeruginosa in VAP. Mortality in this condition is very high. Therefore, new therapeutic and preventive approaches should be sought.

Keywords: bacteremia; multidrug-resistant microorganisms; pneumonia.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Cross Infection* / drug therapy
  • Healthcare-Associated Pneumonia* / complications
  • Healthcare-Associated Pneumonia* / drug therapy
  • Healthcare-Associated Pneumonia* / epidemiology
  • Humans
  • Pneumonia, Ventilator-Associated* / drug therapy
  • Pneumonia, Ventilator-Associated* / epidemiology
  • Pneumonia, Ventilator-Associated* / etiology
  • Staphylococcus aureus

Substances

  • Anti-Bacterial Agents