Degradation of Penicillinic Antibiotics and β-Lactamase Enzymatic Catalysis in a Biomimetic Zn-Based Metal-Organic Framework

Chemistry. 2023 Sep 12;29(51):e202302315. doi: 10.1002/chem.202302315. Epub 2023 Aug 8.

Abstract

Invited for the cover of this issue are Jesús Ferrando-Soria, Donatella Armentano, Antonio Leyva-Pérez, Emilio Pardo and co-workers at University of Valencia, Technical University of Valencia and University of Calabria. The image depicts the crystal structure of a novel ZnII biological metal-organic framework that mimics β-lactamase enzymes. Read the full text of the article at 10.1002/chem.202301325.

MeSH terms

  • Anti-Bacterial Agents
  • Biomimetics*
  • Catalysis
  • Humans
  • Metal-Organic Frameworks*
  • Penicillins
  • Zinc
  • beta-Lactamases

Substances

  • Metal-Organic Frameworks
  • Penicillins
  • beta-Lactamases
  • Anti-Bacterial Agents
  • Zinc