Research Progress of SERS Sensors Based on Hydrogen Peroxide and Related Substances

Crit Rev Anal Chem. 2023 Sep 11:1-22. doi: 10.1080/10408347.2023.2255901. Online ahead of print.

Abstract

Hydrogen peroxide (H2O2) has an important role in living organisms, and its detection is of great importance in medical, chemical, and food safety applications. This review provides a comparison of different types of Surface-enhanced Raman scattering (SERS) sensors for H2O2 and related substances with respect to their detection limits, which are of interest due to high sensitivity compared to conventional sensors. According to the latest research report, this review focuses on the sensing mechanism of different sensors and summarizes the linear range, detection limits, and cellular applications of new SERS sensors, and discusses the limitations in vivo and future prospects of SERS technology for the detection of H2O2.

Keywords: Hydrogen peroxide (H2O2); intracellular sensors; nanozyme; surface-enhanced Raman scattering.

Publication types

  • Review