The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer
Genes Dis. 2023 Apr 28;11(2):542-545.
doi: 10.1016/j.gendis.2023.03.026.
eCollection 2024 Mar.
1 State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China.
2 Departments of Pathology, Characteristic Medical Center of The Chinese People's Armed Police Force, Tianjin 300162, China.
3 Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China.
4 Department of Pathology, Medical School, Dalian University, Dalian, Liaoning 116622, China.
5 School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
6 Department of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin 300121, China.