Recommendations on prevention of infections in patients with T-cell lymphomas: a narrative review and synthesis

Leuk Lymphoma. 2023 Dec;64(13):2057-2070. doi: 10.1080/10428194.2023.2252945. Epub 2023 Sep 9.

Abstract

T/Natural killer (NK) cell lymphomas (TCL) represent a heterogenous subgroup of non-Hodgkin lymphoma, associated with poorer prognosis and higher treatment toxicity. A cohesive synthesis of infection outcomes among TCL patients is lacking. International guidelines offer no specific recommendations regarding prophylaxis or supportive infection care for TCL patients. This systematic narrative review highlights infection outcomes in TCL patients treated with conventional, and novel therapies. Recommendations for infection screening, antimicrobial prophylaxis and vaccination strategies are outined.

Keywords: T cell lymphoma; infectious complications; neoplasia; novel therapies.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Humans
  • Killer Cells, Natural / pathology
  • Lymphoma, Non-Hodgkin* / pathology
  • Lymphoma, T-Cell* / complications
  • Lymphoma, T-Cell* / diagnosis
  • Lymphoma, T-Cell* / therapy