Visible-Light-Driven NO Release from Postmodified MOFs via Photoinduced Electron Transfer for Antibacterial Application

De-Bo Hao; Jia-Li Li; Xian-Chao Zhou; Yan Yan Li; Zhen-Xin Zhao; Rui Zhou

doi:10.1002/smll.202305943

Visible-Light-Driven NO Release from Postmodified MOFs via Photoinduced Electron Transfer for Antibacterial Application

Small. 2024 Jan;20(3):e2305943. doi: 10.1002/smll.202305943. Epub 2023 Sep 8.

Authors

De-Bo Hao^{1

2}, Jia-Li Li³, Xian-Chao Zhou³, Yan Yan Li², Zhen-Xin Zhao¹, Rui Zhou^{3

4}

Affiliations

¹ College of Materials and Chemical Engineering, Henan University of Urban Construction, Pingdingshan, Henan, 467036, China.
² Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, P. R. China.
³ College of Chemistry and Materials Science, Jinan University, Guangzhou, 510632, P. R. China.
⁴ College of Life Science and Technology, Jinan University, Guangzhou, 510632, P. R. China.

PMID: 37681501
DOI: 10.1002/smll.202305943

Abstract

Photoresponsive nitric oxide (NO)-releasing materials (NORMs) enable the spatiotemporal delivery of NO to facilitate their potential applications in physiological conditions. Here two novel metal-organic frameworks (MOFs)-based photoactive NORMs achieved by the incorporation of prefunctionalized NO donors into the photosensitive Fe-MOFs via a postmodification strategy is reported. The modified Fe-MOFs display superior photoactivity of NO release when exposed to visible light (up to 720 nm). Significantly, the visible-light-driven NO release properties are further corroborated by their efficient antibacterial performance.

Keywords: antibacterial; metal-organic frameworks; nitric oxide; photoinduced electron transfer; visible light.

MeSH terms

Anti-Bacterial Agents / pharmacology
Electrons
Light
Metal-Organic Frameworks*
Nitric Oxide

Substances

Metal-Organic Frameworks
Nitric Oxide
Anti-Bacterial Agents

Abstract

MeSH terms

Substances

Grants and funding