Olanzapine Overdose in a Two-Year-Old Girl Resulting in Both High Serum and Plasma Levels

Cureus. 2023 Aug 5;15(8):e43002. doi: 10.7759/cureus.43002. eCollection 2023 Aug.

Abstract

The antipsychotic olanzapine is used increasingly to treat various psychiatric illnesses. Accidental olanzapine overdose is uncommon among children. Here, we report a case of a child presenting with an unexplained coma. Accidental ingestion of olanzapine (20 mg) was confirmed by measurement of drug concentrations in both serum and plasma.

Keywords: blood concentration measurement; impaired consciousness; olanzapine; proper specimen storage; toxicity.

Publication types

  • Case Reports