A case of prostatic metastasis from non-seminomatous testicular cancer

IJU Case Rep. 2023 Jun 27;6(5):274-277. doi: 10.1002/iju5.12602. eCollection 2023 Sep.

Abstract

Introduction: Prostatic metastasis from testicular cancer is extremely rare, with only 10 reported cases, all of which were diagnosed as relapse. Herein, we report the case of a patient with concurrent testicular cancer and prostatic metastasis.

Case presentation: A 57-year-old man presented at our emergency department with urinary retention. A painless mass was found in the right scrotum, and computed tomography showed lung, mediastinal, and liver metastases, and an enlarged prostate. Tumor markers were measured in 2057 U/L lactate dehydrogenase, 2460 mIU/mL human chorionic gonadotrophin, 1303 ng/mL alpha-fetoprotein, and 1.51 ng/mL prostate specific antigen. An orchiectomy and biopsy were performed; the pathological results showed immature teratomas, embryonal carcinomas, choriocarcinomas, and seminomas in the testis, and embryonal carcinomas in the prostate, liver, and mediastinum. The patient refused chemotherapy and died 3 months following diagnosis.

Conclusion: Prostatic metastasis should be considered in cases of dysuria or prostate enlargement in testicular cancers.

Keywords: metastatic testicular cancer; non‐seminomatous testicular cancer; prostatic metastasis; testicular cancer; urinary retention.

Publication types

  • Case Reports