The role of polyploidy in tumorigenesis: confusion versus reality

Med Oncol. 2023 Sep 2;40(10):291. doi: 10.1007/s12032-023-02164-w.

Abstract

This letter serves as a response to Dr. Vladimir F. Niculescu's latest letter, which continues to create misunderstanding regarding the embryonic hypothesis for tumor origins. This communication aims to clarify the new points of confusion raised in his letter.

Keywords: Cancer stem cells; Life code theory; Polyploid giant cancer cells.

Publication types

  • Letter
  • Comment

MeSH terms

  • Biological Evolution
  • Carcinogenesis* / genetics
  • Cell Transformation, Neoplastic / genetics
  • Gene Regulatory Networks*
  • Humans
  • Polyploidy