Aromatization of cyclic hydrocarbons via thioether elimination reaction

Yang Liu; Yingqi Feng; Jinli Nie; Sijie Xie; Xin Pen; Huanliang Hong; Xiuwen Chen; Lu Chen; Yibiao Li

doi:10.1039/d3cc03279e

Aromatization of cyclic hydrocarbons via thioether elimination reaction

Chem Commun (Camb). 2023 Sep 19;59(75):11232-11235. doi: 10.1039/d3cc03279e.

Authors

Yang Liu¹, Yingqi Feng¹, Jinli Nie¹, Sijie Xie¹, Xin Pen¹, Huanliang Hong¹, Xiuwen Chen¹, Lu Chen¹, Yibiao Li¹

Affiliation

¹ School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong Province 529090, China. leeyib268@126.com.

PMID: 37655718
DOI: 10.1039/d3cc03279e

Abstract

Herein, the diversity-oriented aromatization of cyclic hydrocarbons via potassium ethyl xanthogenate (EtOCS₂K)/NH₄I-mediated methylthiyl radical addition and thioether elimination was investigated under transition-metal-free conditions. The methylthiyl radical species were generated in situ via the NH₄I-mediated decomposition of DMSO following which EtOCS₂K promoted the breaking of carbon-sulfur bonds of thioether.