Intravaginal Mesalamine Administration: A Novel Technique for Neovaginal Colitis

J Pediatr Adolesc Gynecol. 2024 Feb;37(1):93-94. doi: 10.1016/j.jpag.2023.08.006. Epub 2023 Aug 30.

Abstract

Objective: We aim to present a novel technique for the treatment of neovaginal diversion colitis (also known as neovaginal colitis).

Case: OT is a 21-year-old cisgender female with a history of VACTERL who underwent a colonic vaginoplasty as an infant. She presented with symptoms indicative of and later diagnosed as neovaginal diversion colitis. The patient underwent a novel regimen of vaginal instillation of mesalamine followed by complete resolution of her symptoms.

Discussion: The following case study demonstrates a potentially effective treatment for cases of neovaginal diversion colitis.

Keywords: Colitis; Colonic vaginoplasty; Neovagina; Neovaginal colitis; Neovaginal diversion colitis; VACTERL; Vaginoplasty.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravaginal
  • Adult
  • Colitis* / surgery
  • Female
  • Humans
  • Mesalamine / therapeutic use
  • Plastic Surgery Procedures*
  • Vagina / surgery
  • Young Adult

Substances

  • Mesalamine