The Applications of 2D Materials for Electrochemical Biosensing, Drug Delivery, and Environmental Monitoring

Curr Top Med Chem. 2023;23(15):1426-1447. doi: 10.2174/1568026623666230328125711.

Abstract

Two-dimensional (2D) nanomaterials (NMs) have diverse mechanical, chemical and optical properties due to which they have received a lot of attention in various fields such as biosensors, imaging, tissue engineering, drug delivery, etc. A thorough understanding of the synthetic procedure, physical properties and electrochemical properties of 2D materials will be quite useful in the development of novel and high-efficient electrocatalysts for the electroanalytical application of our interest. This review article summarises the synthesis and application of graphene, graphitic carbon nitride, transition metal dichalcogenides and phosphorene for electrochemical biosensing, drug delivery application and environmental monitoring. Numerous synthetic approaches which have been adopted to synthesize the 2D materials have been covered and discussed. Also, the reasons behind the catalytic activity of various types of 2D materials and their application as electrode modifier for the development of an efficient biosensor for the point-of-care analysis of biomolecule and drug delivery and environmental monitoring have been discussed in detail. This review article will give valuable information and future insights to the researchers working in the field of biosensor, drug delivery and environmental monitoring. We anticipate that this review may be of significance for the field to understand the properties as well as the electroanalytical applications of 2D materials, especially in biosensing, drug and environmental monitoring.

Keywords: 2D Materials; Biosensing; Diagnostics; Drug detection; Electrode Modification; NMs.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems
  • Electrodes
  • Environmental Monitoring*
  • Nanostructures*
  • Point-of-Care Systems