Severe problem of macrolides resistance to common pathogens in China

Jialin Li; Lesen Liu; Hua Zhang; Jing Guo; Xiaoling Wei; Min Xue; Xiang Ma

doi:10.3389/fcimb.2023.1181633

Severe problem of macrolides resistance to common pathogens in China

Front Cell Infect Microbiol. 2023 Aug 10:13:1181633. doi: 10.3389/fcimb.2023.1181633. eCollection 2023.

Authors

Jialin Li^{1

2}, Lesen Liu³, Hua Zhang^{1

2}, Jing Guo^{1

2}, Xiaoling Wei^{1

2}, Min Xue^{1

2}, Xiang Ma^{1

2}

Affiliations

¹ Department of Respiratory Disease, Children's Hospital Affiliated to Shandong University, Jinan, Shandong, China.
² Jinan Key Laboratory of Pediatric Respiratory Diseases, Jinan Children's Hospital, Jinan, China.
³ Surgical Department, Huaiyin People's Hospital, Jinan, China.

Abstract

With the widespread use of macrolide antibiotics in China, common pathogens causing children's infections, such as Streptococcus pneumoniae, Streptococcus (including Group A streptococcus, Group B streptococcus), Staphylococcus aureus, Bordetella pertussis, and Mycoplasma pneumoniae, have shown varying degrees of drug resistance. In order to provide such problem and related evidence for rational use of antibiotics in clinic, we reviewed the drug resistance of common bacteria to macrolides in children recent 20 years.

Keywords: China; bacteria; child; macrolides; resistance.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents* / pharmacology
Anti-Bacterial Agents* / therapeutic use
Bacteria* / drug effects
Bacteria* / isolation & purification
Bacteria* / pathogenicity
Bacterial Infections* / drug therapy
Bacterial Infections* / microbiology
Child
China
Drug Resistance, Bacterial*
Humans
Macrolides* / pharmacology
Macrolides* / therapeutic use

Substances

Macrolides
Anti-Bacterial Agents

Grants and funding

This work was supported by grants from Key Laboratory of Pediatric Respiratory Disease in Jinan Children’s Hospital and Shandong Provincial Clinical Research Center for Children’s Health and Disease (SDPRC009).