Challenging diagnosis of Mycolicibacterium cosmeticum/canariasense infection: A case report and literature review

Daniel Grupel; Orly Sagi; Israel Nissan; Rona Grossman; Motro Yair; Jacob Moran-Gilad; Dana Danino

doi:10.1016/j.jctube.2023.100393

Challenging diagnosis of Mycolicibacterium cosmeticum/canariasense infection: A case report and literature review

J Clin Tuberc Other Mycobact Dis. 2023 Aug 12:33:100393. doi: 10.1016/j.jctube.2023.100393. eCollection 2023 Dec.

Authors

Daniel Grupel^{1

2}, Orly Sagi^{2

3}, Israel Nissan⁴, Rona Grossman⁴, Motro Yair², Jacob Moran-Gilad^{2

3}, Dana Danino^{2

5}

Affiliations

¹ Soroka University Medical Center, Infectious Disease Unit, Beer-Sheva, Israel.
² Ben-Gurion University of the Negev, Faculty of Health Sciences, Beer-Sheva, Israel.
³ Soroka University Medical Center, Microbiology Laboratory, Beer-Sheva, Israel.
⁴ Public Health Services, National Public Health Laboratory, Ministry of Health, Tel Aviv, Israel.
⁵ Soroka University Medical Center, Pediatric Infectious Disease Unit, Beer-Sheva, Israel.

Abstract

We present the case of an immunocompromised child with Mycolicibacterium cosmeticum/ canariasense infection. Our case highlights the difficulty in adequate speciation. Most isolates described in the literature were identified using 16 s-rRNA PCR, which if performed on our sample would at best be inconclusive. Misidentifications could have a real impact on the body of evidence collected on these isolates thus far.

Keywords: Mycobacteriaceae; Mycolicibacterium canariasense; Mycolicibacterium cosmeticum.

Publication types

Case Reports