Calcification detection on upper extremity arteries: a comparison of ultrasonic and X-ray methods

PeerJ. 2023 Aug 23:11:e15855. doi: 10.7717/peerj.15855. eCollection 2023.

Abstract

Background: Vascular calcification (VC) has been observed in patients with hemodialysis, whereas few studies have investigated calcification in the upper extremity vasculature. Both ultrasound and X-ray are used to investigate the calcification of arteries in patients. However, there is a lack of data on the consistency between these two methods. The aim of this study was to investigate the occurrence of VC in the radial and ulnar arteries of hemodialysis patients and investigate the detection consistency in VC between ultrasound and X-ray.

Methods: Ultrasound and X-ray examinations were performed in the radial and ulnar arteries of both the left and right upper extremities of 40 patients on hemodialysis. The calcification status of arteries was evaluated by the calcification index from ultrasound and X-ray respectively. Clinical variables of patients were collected from all the involved patients.

Results: Of the 40 patients, VC was detected in 31 patients by ultrasound, while X-ray detected VC in 22 patients. Compared to ultrasound assessment, X-ray assessment was 73.21% sensitive but only 66.35% specific with a positive predictive value of 53.95% for detecting calcifications in the radial or ulnar artery. The level of agreement between ultrasound and X-ray results was fair. In addition, our data showed that more ulnar arteries had VCs than the corresponding radial arteries.

Conclusion: Ultrasound is more sensitive in detecting the presence of calcified atherosclerotic lesions. Ultrasound and X-ray exhibited fair consistency. Ultrasound screening for upper extremity radial and ulnar arteries in hemodialysis patients may deserve attention to explore its clinical significance.

Keywords: Hemodialysis; Radial artery; Ulnar artery; Ultrasound; Vascular calcification; X-ray plain film.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Ulnar Artery / diagnostic imaging
  • Ultrasonics*
  • Upper Extremity / diagnostic imaging
  • Vascular Calcification* / diagnostic imaging
  • X-Rays

Associated data

  • ChiCTR/ChiCTR1900021975

Grants and funding

This project was supported by the Key Research Program of Hebei Province, China (Grant No. 21377747D) and by the Medical Science and Research Program of the Health Commission of Hebei Province, China (Grant No. 20221370). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.