Topology-sensitive weighting model for myocardial segmentation

Comput Biol Med. 2023 Oct:165:107286. doi: 10.1016/j.compbiomed.2023.107286. Epub 2023 Aug 8.

Abstract

Accurate myocardial segmentation is crucial for the diagnosis of various heart diseases. However, segmentation results often suffer from topology structural errors, such as broken connections and holes, especially in cases of poor image quality. These errors are unacceptable in clinical diagnosis. We proposed a Topology-Sensitive Weight (TSW) model to keep both pixel-wise accuracy and topological correctness. Specifically, the Position Weighting Update (PWU) strategy with the Boundary-Sensitive Topology (BST) module can guide the model to focus on positions where topological features are sensitive to pixel values. The Myocardial Integrity Topology (MIT) module can serve as a guide for maintaining myocardial integrity. We evaluate the TSW model on the CAMUS dataset and a private echocardiography myocardial segmentation dataset. The qualitative and quantitative experimental results show that the TSW model significantly enhances topological accuracy while maintaining pixel-wise precision.

Keywords: Echocardiography; Myocardial Segmentation; Persistent Homology; Topology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Echocardiography
  • Heart Diseases*
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Myocardium