Alloplastic reconstruction of the mandible after subtotal mandibulectomy for medication-related osteonecrosis of the jaw: An update of the method

Head Neck. 2023 Oct;45(10):2638-2648. doi: 10.1002/hed.27489. Epub 2023 Aug 25.

Abstract

Background: Reconstruction of continuity defects following osteonecrosis in multimorbid patients is challenging. In all cases of the predescribed palliative treatment method for alloplastic mandible reconstruction, plate fractures were detected in follow-up. We hypothesized that a modification could avoid these fractures, leading to stable long-term results.

Methods: This retrospective study compares the original method with a modification using single, laser-sintered CAD-CAM plates instead of manually bent miniplates. The predescribed shuttering technique was used to reconstruct the mandible in its original shape with bone cement.

Results: Uneventful wound healing was observed in 86% of the cases after modification of the method. No implant or plate fracture occurred.

Conclusions: The presented method should be considered as a treatment option for mandible reconstruction in elderly, multimorbid patients in palliative situations. The results of this study suggest that the modification of the method leads to significantly improved long-term stability. Donor site morbidity is avoided with this method of palliative surgery.

Keywords: ARONJ; MRONJ; Palacos® reconstruction; alloplastic reconstruction; mandible reconstruction; medication-related osteonecrosis of the jaw.

MeSH terms

  • Aged
  • Bisphosphonate-Associated Osteonecrosis of the Jaw* / surgery
  • Humans
  • Mandible / surgery
  • Mandibular Osteotomy / methods
  • Mandibular Reconstruction* / methods
  • Osteonecrosis* / surgery
  • Retrospective Studies