Cidofovir in Severe Hypoxemic Adenoviral Pneumonia

Aditi Gupta; Pooja Khanna; Arjun Parihar; Dhirendra Pratap Singh; Sunit Chandra Singhi

doi:10.1007/s12098-023-04812-5

Cidofovir in Severe Hypoxemic Adenoviral Pneumonia

Indian J Pediatr. 2024 Apr;91(4):398-400. doi: 10.1007/s12098-023-04812-5. Epub 2023 Aug 25.

Authors

Aditi Gupta¹, Pooja Khanna¹, Arjun Parihar¹, Dhirendra Pratap Singh², Sunit Chandra Singhi³

Affiliations

¹ Department of Pediatrics, Amrita Hospital, Mata Amritanandamayi Marg, Sector 88, Faridabad, Haryana, 121002, India.
² Department of Pediatric Critical Care, Amrita Hospital, Mata Amritanandamayi Marg, Sector 88, Faridabad, Haryana, 121002, India.
³ Department of Pediatrics, Amrita Hospital, Mata Amritanandamayi Marg, Sector 88, Faridabad, Haryana, 121002, India. sunit.singhi@gmail.com.

PMID: 37620591
DOI: 10.1007/s12098-023-04812-5

Abstract

The authors present a 16-mo-old boy with flu like symptoms, not responding to supportive management and progressed to severe hypoxemic pneumonia. Adenovirus was detected in the nasopharyngeal aspirate. He showed rapid improvement after intravenous cidofovir administration.

Keywords: Adenovirus; Cidofovir; Immunocompetent child; Severe hypoxemic pneumonia.

MeSH terms

Adenoviridae Infections* / diagnosis
Antiviral Agents / therapeutic use
Cidofovir / therapeutic use
Cytosine / therapeutic use
Humans
Male
Organophosphonates* / therapeutic use
Pneumonia, Viral*

Substances

Cidofovir
Antiviral Agents
Organophosphonates
Cytosine