Draft genome sequence of Enterobacter cloacae ST473 harbouring bla CMH-3 isolated from a human patient diagnosed with recurrent bacteriuria in Nigeria

Access Microbiol. 2023 Jul 6;5(7):acmi000565.v3. doi: 10.1099/acmi.0.000565.v3. eCollection 2023.

Abstract

Enterobacter cloacae is among the most frequently isolated species described in clinical infections and is commonly associated with a multidrug resistance (MDR) phenotype. We present the draft genome sequence of a MDR E. cloacae isolated in Nigeria from the urine sample of an adult male outpatient diagnosed with symptomatic recurrent bacteriuria. The isolate was found to be resistant to ceftriaxone, cefotaxime, cefepime and levofloxacin. Genome analysis revealed the presence of the beta-lactamase chromosomal gene blaCMH-3, which may be responsible for the antibiotic resistance observed in the recurrent E. cloacae urinary tract infection.

Keywords: Enterobacter cloacae; extended-spectrum beta-lactamases; urinary tract infection.