Safety of direct oral anticoagulant use in patients taking verapamil or diltiazem

Heart Rhythm. 2023 Dec;20(12):1793-1795. doi: 10.1016/j.hrthm.2023.08.017. Epub 2023 Aug 19.
No abstract available

Keywords: Cytochrome P-450 CYP3A; Direct-acting oral anticoagulant; Enzyme Inhibitor; Hemorrhage; P-glycoprotein; Safety.

MeSH terms

  • Administration, Oral
  • Anticoagulants / adverse effects
  • Calcium Channel Blockers
  • Diltiazem* / adverse effects
  • Humans
  • Verapamil* / adverse effects

Substances

  • Diltiazem
  • Verapamil
  • Anticoagulants
  • Calcium Channel Blockers