Nanobiopesticides: Are they the future of phytosanitary treatments in modern agriculture?

Abstract

The world's population is continuously increasing; therefore, food availability will be one of the major concerns of our future. In addition to that, many practices and products used, such as pesticides and fertilizers have been shown harmful to the environment and human health and are assumed as being one of the main factors responsible for the loss of biodiversity. Also, climate change could agravate the problem since it causes unpredictable variation of local and regional climate conditions,which frequently favor the growth of diseases, pathogens and pest growth. The use of natural products, like essential oils, plant extracts, or substances of microbial-origin in combination with nanotechnology is one suitable way to outgrow this problem. The most often employed natural products in research studies to date include pyrethrum extract, neem oil, and various essential oils, which when enclosed shown increased resistance to environmental factors. They also demonstrated insecticidal, antibacterial, and fungicidal properties. However, in order to truly determine if these products, despite being natural, would be hazardous or not, testing in non-target organisms, which are rare, must start to become a common practice. Therefore, this review aims to present the existing literature concerning nanoformulations of biopesticides and a standard definition for nanobiopesticides, their synthesis methods and their possible ecotoxicological impacts, while discussing the regulatory aspects regarding their authorization and commercialization. As a result of this, you will find a critical analysis in this reading. The most obvious findings are that i) there are insufficient reliable ecotoxicological data for risk assessment purposes and to establish safety doses; and ii) the requirements for registration and authorization of these new products are not as straightforward as those for synthetic chemicals and take a lot of time, which is a major challenge/limitation in terms of the goals set by the Farm to Fork initiative.

Keywords: Biopesticides; Ecotoxicological risk assessment; Nanomaterials synthesis; Natural compounds; Regulation.