Impact of gastrointestinal polymerase chain reaction panels on antibiotic utilization in hospitalized adult patients

Gillean A Kelly; Roumen Iordanov; Alex Franklin; Amna Ahmed; Krithika Srinivasan; Jesica Hayon; Todd Lasco; Rosie Amini; Sabra Shay; Prathit A Kulkarni; Mayar Al Mohajer

doi:10.1017/ash.2023.174

Impact of gastrointestinal polymerase chain reaction panels on antibiotic utilization in hospitalized adult patients

Antimicrob Steward Healthc Epidemiol. 2023 Aug 2;3(1):e135. doi: 10.1017/ash.2023.174. eCollection 2023.

Authors

Gillean A Kelly^{1

2}, Roumen Iordanov³, Alex Franklin³, Amna Ahmed³, Krithika Srinivasan³, Jesica Hayon³, Todd Lasco⁴, Rosie Amini⁵, Sabra Shay⁵, Prathit A Kulkarni^{3

6}, Mayar Al Mohajer³

Affiliations

¹ Baylor College of Medicine, School of Medicine, Houston, Texas.
² University of Texas Health Science Center at Houston, School of Public Health, Houston, Texas.
³ Baylor College of Medicine, Department of Medicine, Section of Infectious Diseases, Houston, Texas.
⁴ Baylor College of Medicine, Department of Pathology & Immunology, Houston, Texas.
⁵ Premier Inc., Department of Clinical Intelligence, Charlotte, North Carolina.
⁶ Michael E. DeBakey Veterans Affairs Medical Center, Medical Care Line, Houston, Texas.

Abstract

Multiplex stool polymerase chain reaction (PCR) panels offer rapid comprehensive testing for patients with infectious diarrhea. We compared antibiotic utilization among hospitalized patients with suspected infectious diarrhea who underwent diagnostic testing with either a stool culture or stool PCR panel. No significant differences in antibiotic utilization were identified.