Same-gender differences in perioperative complications and transfusion management for lower limb arthroplasty

BMC Musculoskelet Disord. 2023 Aug 16;24(1):653. doi: 10.1186/s12891-023-06788-x.

Abstract

Introduction: Total hip (THA) and knee arthroplasty (TKA) are surgical interventions for patients with primary and posttraumatic osteoarthritis. The present clinical investigation compared gender differences in THA and TKA.

Methods: Data from 419 patients following primary THA and TKA were collected. The occurrence of systemic and surgery-related complications, the units of blood transfused, and the change in Hb were investigated. Hb was collected preoperatively and at 1, 2, 4 and 7 days postoperatively. Statistical analysis was performed using the software IBM SPSS 28.

Results: There was no significant difference in surgery-related and general complications in men between THA and TKA. A significant difference between THA and TKA in systemic complications in women was observed. No significant difference between THA and TKA in related to surgery-related complications was evidenced. In men, no difference in Hb progression was observed. In women, a significant Hb drop was evidenced (p = 0.03). The rate of blood transfusion units in women was significantly greater in TKA than in THA (p = 0.001). No statistically significant difference was observed in men in the rate of transfusion between THA and TKA.

Conclusion: Perioperative care should be organized differently for women and men. Furthermore, a differentiation between the procedures for each sex could prevent the occurrence of perioperative complicated courses.

Keywords: Blood transfusion; Complications; Gender differences; THA; TKA.

MeSH terms

  • Arthroplasty, Replacement, Knee* / adverse effects
  • Blood Transfusion
  • Female
  • Humans
  • Lower Extremity
  • Male
  • Osteoarthritis*
  • Sex Factors