Granulocytic Sarcoma Mimicking Cholesteatoma: Beware the Temporal Bone in Haematological Patients

ORL J Otorhinolaryngol Relat Spec. 2023;85(5):299-304. doi: 10.1159/000532080. Epub 2023 Aug 16.

Abstract

Granulocytic sarcoma is a myeloid neoplasm that can occur in isolation or in association with acute leukaemia. The temporal bone represents a sanctuary site for myeloid progenitors: granulocytic sarcoma may develop in this location before or concomitantly with the onset of acute leukaemia. This atypical presentation with clinical and radiological data that closely mimic those of cholesteatoma often delays an accurate diagnosis. We here describe the clinical case of a 28-year-old male with granulocytic sarcoma of the external auditory canal that preceded the relapse of promyelocytic leukaemia.

Keywords: Acute leukaemia; Case report; External auditory canal tumour; Granulocytic sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Leukemia*
  • Male
  • Neoplasm Recurrence, Local
  • Sarcoma, Myeloid* / diagnosis
  • Temporal Bone / diagnostic imaging